About megatomi.com
About megatomi.com
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Promptly acquire sections as slim or thick as your software involves, without worrying about losing or distorting valuable tissue samples.
Megatome can be a vibrating microtome intended to portion a broad choice of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With substantial blade vibrating frequency and minimized blade deflection, Megatome permits higher-throughput tissue sectioning with uniform surface area profile, together with minimal tissue injury and data decline.
Antibodies may perhaps acquire months to diffuse through just a few millimeters of tissue, having a steep labeling gradient from surface to Main.
Functioning the CLI directly from a Gradle activity will not be now supported. A distribution have to be established via gradlew :j2d-cli:distZip to create a zip file that contains anything required to run.
SE uses a rotational electric subject to disperse remarkably electromobile molecules (like antibodies or surfactant micelles) through a porous sample without the need of damaging electrically charged constructions in the tissue. This allows two-4 day clearing of intact organs,
Our preformulated EasyIndex Option raises and homogenize the refractive index of delipidated tissue samples, rendering them fully transparent. This enables light penetration in to the sample and guarantees the acquisition of substantial-resolution, in-concentration graphic details.
Megatome is really a novel microtome that allows for high-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with negligible tissue problems and data reduction.
eFLASH is actually a fast tissue labeling method that allows for uniform full-organ staining in twenty rounds of labeling.
Totally delipidate whole mouse brains or comparably sized samples in only one working day with SmartBatch+, or in one week with our passive clearing package.
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Protect avoids the variability of hydrogel embedding and the data reduction from PFA preservation, protecting specimens for a number of rounds of processing.
Leverage the Obvious+ tissue clearing method, as well as eFLASH and patented stochastic electrotransport technologies, to swiftly apparent and label complete organs. Important highlights and options contain:
Our novel Protect tissue preservation approach sorts intramolecular bonds utilizing polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.